Tag: Jennifer Phillips-Cremins
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“Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis”
Jennifer E. Phillips-Cremins, Associate Professor of Genetics, has contributed to a new paper in Neuron. Abstract: We examined the role of repeat expansions in the pathogenesis of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) by analyzing whole-genome sequence data from 2,442 FTD/ALS patients, 2,599 Lewy body dementia (LBD) patients, and 3,158 neurologically healthy subjects.…
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Jennifer Phillips-Cremins Uses Light to Serve Up On-demand Genome Folding
Every cell in your body has a copy of your genome, tightly coiled and packed into its nucleus. Since every copy is effectively identical, the difference between cell types and their biological functions comes down to which, how and when the individual genes in the genome are expressed, or translated into proteins. Jennifer Phillips-Cremins, assistant…