Category: Publishing

Presidential Assistant Professor Cesar de la Fuente, has a new paper out in ACS Nano. Abstract: Encrypted peptides have been recently found in the human proteome and represent a potential class of antibiotics. Here we report three peptides derived from the human apolipoprotein B (residues 887–922) that exhibited potent antimicrobial activity against drug-resistant Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococci both in…

Danielle Basset has a new paper out in PNAS! Abstract Many complex networks depend upon biological entities for their preservation. Such entities, from human cognition to evolution, must first encode and then replicate those networks under marked resource constraints. Networks that survive are those that are amenable to constrained encoding—or, in other words, are compressible.…

The Riggleman Group has published a new study in PNAS! Abstract Advances in polymer chemistry over the last decade have enabled the synthesis of molecularly precise polymer networks that exhibit homogeneous structure. These precise polymer gels create the opportunity to establish true multiscale, molecular to macroscopic, relationships that define their elastic and failure properties. In…

The Perdikaris Group has a new paper available at arxiv.org/abs/2201.01032 Abstract: Supervised operator learning is an emerging machine learning paradigm with applications to modeling the evolution of spatio-temporal dynamical systems and approximating general black-box relationships between functional data. We propose a novel operator learning method, LOCA (Learning Operators with Coupled Attention), motivated from the recent…

Abstract Flexible Polymeric Nanoparticles In article number 2101290, Samaneh Farokhirad, Ravi Radhakrishnan, and co-workers explore the biophysical principles behind the effect of shape, chemistry, and flexibility of nanoparticles on multivalent ligand–receptor-mediated avidity and cellular uptake. The findings help establish rational design principles that confer tension, membrane excess area, and cytoskeletal sensing properties to the nanoparticles, which…

 César de la Fuente, Presidential Assistant Professor in Bioengineering, Microbiology, Psychiatry, and Chemical and Biomolecular Engineering, and his group have a new paper out in Nature Methods. Abstract The emergence of drug-resistant bacteria calls for the discovery of new antibiotics. Yet, for decades, traditional discovery strategies have not yielded new classes of antimicrobial. Here, by…

Robert Riggleman, Associate Professor of Chemical and Biomolecular Engineering, and members of his group have published a new paper in Science Advances. Abstract Through a combined approach of experiment and simulation, this study quantifies the role of entanglements in determining the mechanical properties of glassy polymer blends. Uniaxial extension experiments on 100-nm films containing a bidisperse…

Professor César de la Fuente, Presidential Assistant Professor Bioengineering, Chemical and Biomolecular Engineering, Microbiology and Psychiatry, has a new paper which discusses a diagnostic test that detects SARS-CoV-2 within 6.5 min and costs $1.50 per unit to produce.